ABOUT US
As a group of scientific researchers working on various projects in human health, we realised that our research was united by common themes surrounding ageing, age-related diseases and health span longevity. Recognising the interdisciplinary nature of this field, we decided to collaborate and draw on our experience in pathology, biochemistry, physiology, nutrition and genetics to tackle some of the most pressing health challenges facing the world today: Diabetes, cancer, Alzheimer's disease, Parkinson's disease, cardiovascular disease and liver disease. We are particularly interested in understanding the immunological and metabolic mechanisms that underpin these diseases, with the goal of figuring out how to keep people younger and healthier for longer.
Biochemistry, Pathology, Ketogenic Metabolic Therapy, Nutrition
Dr Isabella D. Cooper
Human ex vivo and in vitro wet lab and clinical trials scientist: Isabella is a biochemist, medical pathologist and ketogenic specialist. Her research focuses on ageing biology, ketogenic science, hyperinsulinemia, and chronic diseases including cancer, Alzheimer’s, cardiovascular and autoimmune diseases.
Isabella’s PhD elucidated the first full spectrum metabolic, endocrine, lipidology LDL responses and extracellular vesicles phenotypes, in cross-over clinical trials with participants in different metabolic states. She published a diagnostic grading scale for metabolic phenotypes and classified and named the disease Hyperinsulinaemia-Osteofragilitus in MDPI Medical Dictionary.
Isabella is a Member of and accredited with; the Royal Society of Biology; Endocrine Society; Biochemical Society, and Physiological Society and an Associate Fellow of The Higher Education Academy. She holds a BSc (Hons) in Biochemistry with Medical Physiology, molecular genetics, advanced cell and cancer biology, neurology, endocrinology and immunology, protein and enzyme biochemistry, bioinformatics in influenza and metabolic biochemistry. She has won multiple awards including the Faculty of Science and Technology Awards, Individual Teaching Award and Group Teaching Award for Medical Pathophysiology, multiple Dean’s List Awards and the UK Biochemical Society Award.
Dr Cooper is published in the British Medical Journal, Frontiers Cardiovascular Disease, International Journal of Molecular Sciences, Biomedicines, Antioxidants, Frontiers Nutrition, Journal of Oncology, HART and The Brownstone Institute.
Dr Cooper is on the Scientific Advisory Board of: PHC (Public Health Collaboration); HART; and KetoLive, a Swiss Medical Association and German Medical Society continued medical eduction accreditation institute.
Biochemistry, Pathology, Immunology
Dr Lucy Petagine
Human ex vivo and in vitro post-doctoral scientist: Lucy is a Biochemist and Immunologist with a focus on the pathobiology and metabolism of liver diseases, including how exogenous and endogenous toxins may accelerate cellular ageing and disease progression.
Lucy’s PhD thesis investigated the inflammatory pathways in alcohol-associated liver disease, understanding how oxidative stress, mitochondrial function and cell death underpin the progression of disease. She also investigated novel nanoformulation-based treatments encapsulating Curcumin, in collaboration with UCL School of Pharmacy, to establish their protection against oxidative stress and liver injury.
Lucy completed her PhD in Biochemistry and Pathology, majored with Honours in her Bachelor’s in Biomedical Science and has a Masters degree with Merit in Immunology. from Imperial College London. She was also awarded the Jan Campbell Prize during her BSc and is also an Associate Fellow of the Higher Education Academy.
Dr Petagine has published various articles and reviews including topics such as metabolic dysfunction-associated steatotic liver disease, a condition afflicting young adults increasing the risk of cardiovascular disease.
Lucy has extensive experience in biochemical and immunological assays as well as analysis of large UK BioBank datasets and in proficient in R programming language.
Physiology, Nutrition
Dr Yvoni Kyriakidou
Human clinical trials Research Fellow: Yvoni specialises in exercise physiology investigating musculoskeletal system changes associated with ageing and age-related diseases. She is an expert in ex vivo studies and techniques to show metabolic and immunological changes in muscle tissues. Yvoni’s PhD focused on nutritional strategies and supplementation ameliorating muscle damage and function, and exercise-induced inflammation in younger and older adults. Her research interests also focus on the physiological pathways that lead to increased performance during specific exercise protocols as well as how ageing affects muscle function, human performance and health.
Dr Kyriakidou has published in Frontiers in Physiology, European Journal of Applied Physiology, MDPI and Journal of the International Society of Sports Nutrition. She has also presenting her research at national and international conferences including the World Congress on Exercise is Medicine ®.
Yvoni has a PhD in Exercise Physiology and Sports & Exercise Nutrition, a MSc Sports Nutrition and BSc Nutrition & Dietetics and is a Research Fellow at the University of Westminster and Associate Fellow of the Higher Education Academy. She is also a registered Associate Nutritionist of the Association for Nutrition, Affiliate of The Physiological Society, and Endocrine Society. Multiple funding awards, including the Globally Engaged Research Scholarship and the Ignite Fund, and Affiliate grant from The Physiological Society to present her research in national and international conferences in the United States.